双羟萘酸噻嘧啶|22204-24-6
双羟萘酸噻嘧啶|22204-24-6
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双羟萘酸噻嘧啶(原料药)厂家、价格|CAS#22204-24-6

英文名称:Pyrantel pamoate
中文别名:双羟乃酸噻嘧啶;双羟萘酸噻嘧啶;(E)-1-甲基-2-[2-(2-噻吩基)乙烯基]-1,4,5,6-四氢嘧啶 4,4'-亚甲基-双(3-羟基2-奈酸)盐;恩波酸噻嘧啶;抗虫灵
分子式:C34H30N2O6S
分子量:594.68
CAS 号: 22204-24-6

性    状:黄色褐色晶体粉末
含    量:97%
包    装:20kg/纸板桶
标    准:部()标准

功能主治:
作用是通过抑制胆碱酯酶,使虫体肌肉强烈收缩,并导致痉挛性麻痹;但不引起蛔虫骚动。 本品是去极化神经肌肉阻滞剂,
具有明显的烟碱样活性,也能抑制胆碱酯酶,使乙酰胆碱堆积,导致虫体痉挛性麻痹而排出体外;另外,它可使虫体单个细
胞去极化,峰电位发放频率增加,肌张力亦增加,使虫体失去自主活动。 与哌嗪不同的是其作用快,先显著收缩,其后麻痹
不动。 蛔虫、钩虫、蛲虫及其混合感染,以驱钩虫疗效。

用量用法:
驱钩虫、蛔虫:口服,1.2g~1.5g/日。小儿每日30mg/kg。睡前1次顿服。不必服用泻药。驱钩虫应连服3日。驱蛲虫:1.5g/
日,每晚顿服,连服3日(由于未成熟蛲虫对噻嘧啶的敏感性差,故应在疗程两周后,待幼虫成熟,再进行疗程)。肛
用软膏,每晚睡前涂于肛门周围,再插入肛内挤出1g即可,连用7日。 宝塔糖:(1)成人常用量①蛔虫病,一次按体重
10mg/kg(一般为500mg)顿服,每日一次,疗程1-2日;②钩虫感染,剂量同上,连服3日;③蛲虫感染,每日按体重5-10mg/kg
,连服7日。 (2)小儿常用量①蛔虫病,每日按体重10mg/kg,睡前顿服,连服2日;②钩虫病,剂量同上,连服3日;③蛲
虫病,每日按体重10mg/kg,睡前顿服,连服一周。


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Pyrantel pamoate (API) manufacturers, price | CAS # 22204-24-6

English name: Pyrantel pamoate
Chinese Alias: Double hydroxyl acid is pyrantel; pyrantel pamoate; (E) -1- methyl-2- [2- (2-thienyl) vinyl] 1,4,5,6-four pyrimidine hydrogen 4,4'-methylene - bis (3-hydroxy-2- Chennai acid) salt; Ein acid pyrantel; pyrantel pamoate
Molecular formula: C34H30N2O6S
Molecular Weight: 594.68
CAS: 22204-24-6

Appearance: yellow to brown crystalline powder
Content: 97%
Packing: 20kg / drum
Standard: section (professional) standards

Indications:
By inhibiting cholinesterase, so that the parasite strong muscle contractions and cause spastic paralysis; roundworms, but not cause a stir. This product is depolarizing neuromuscular blocking agents,
Has obvious nicotinic activity can also inhibit cholinesterase, acetylcholine accumulation, resulting in spastic paralysis and parasite excreted; in addition, it allows the parasite single fine
Cell depolarization peak potential firing frequency increased muscle tension also increased, so that the worm loses locomotor activity. Piperazine different is its rapid onset of action first significant contraction, followed by paralysis
Do not move. Roundworm, hookworm, pinworm and mixed infections, hookworm drive to best effect.

Consumption usage:
Drive hookworm, roundworm: oral, 1.2g ~ 1.5g / day. Children daily 30mg / kg. 1 Dayton clothing before going to bed. You do not need to take laxatives. Hookworm should drive even for 3 days. Flooding pinworm: 1.5g /
Day, night Dayton clothing, even for 3 days (due to the sensitivity of immature pinworm pyrantel difference, it should be after the first course of treatment for two weeks, until the larvae mature, and then a second course of treatment). anus
Ointments, applied around the anus every night before bed, and then you can insert extrusion 1g, once on the 7th anal. Pagoda sugar: (1) The usual dose for adults ① ascariasis, once according to body weight
10mg / kg (usually 500mg) Dayton clothing, once daily for 1-2 days; ② hookworm infection dose ibid., Even for 3 days; ③ pinworm infection, daily weight 5-10mg / kg
For 7 days. (2) Pediatric usual dose ① ascariasis, daily weight 10mg / kg, Dayton clothing before going to bed, and even served on the 2nd; ② hookworm dose ibid., Even for 3 days; ③ Nao
Echinococcosis, daily weight 10mg / kg, Dayton clothing before going to bed, and even served a week.


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